Warning: This product has not been approved or cleared for marketing by the U.S. Food and Drug Administration and is considered an investigational device.
Click here

Publications

Peer Reviewed Articles

Chiang JC, Wu M, Lee JH, et al. Impact of an ophthalmic cooling device on corneal immune and sensory nerve features in chronic ocular surface pain: a prospective, feasibility study. Ophthalmol Ther. Published online 2026. doi:10.1007/s40123-026-01454-6

Galor, A., Rapuano, C., Epitropoulos, A. et al. A Randomized Double-Masked Study Evaluating Safety and Efficacy of a Novel Topical Cooling Device for Chronic Ocular Surface Pain. Ophthalmol Ther (2026). https://doi.org/10.1007/s40123-026-01392-3

Galor A, Henderson B, Ifantides C, Stefater JA, Stryjewski TP. The Safety and Tolerability of a Single Scleral Treatment With a Cooling Device in Rabbits. Transl Vis Sci Technol. 2025;14(10):2. doi:10.1167/tvst.14.10.2

Galor A, Abbott K, Henderson B, et al. Chronic Ocular Surface Pain: An Optometrist and Ophthalmologist Survey. Ophthalmol Ther. 2025;14(11):2801-2818. doi:10.1007/s40123-025-01234-8

Accepted Abstracts

Ifantides C, Hinds M, Nguyen T, Rapuano C, Hinds A, Duhig G, Stevens A, Samarawickrama C, Henderson B, Wu H, Gupta P, Galor A. Improved Corneal Sensitivity After Treatment with a Novel Topical Ophthalmic Cooling Device in Patients with Chronic Ocular Surface Pain. Accepted for presentation at: Association for Research in Vision and Ophthalmology Annual Meeting; May 2026; Denver, CO.

Chiang J C B, Curkpatrick A, Galor A, Thompson V, Lindstrom R, Ifantides C, Nguyen T, Lee J H, Downie L E. Effects of a topical ophthalmic cooling device for chronic ocular surface pain on the ocular surface and corneal nerves. Accepted for presentation at: Association for Research in Vision and Ophthalmology Annual Meeting; May 2026; Denver, CO.

Epitropoulos AT, Dhaliwal DK, Jackson MA, McDonald MB, Periman LM, Galor A. In vivo confocal microscopy of the corneal surface in eyes treated with a novel ocular cooling device for chronic ocular surface pain. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC.

Garg S, Sadri E, Loh J, Hovanesian JA, Periman LM, Desai NR. Safety and tolerability of repeat treatments in rabbit and pig eyes using a novel topical ocular cooling device for ocular pain. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC.

White D E, Tonk R S, Venkateswaran N, Zhu D, Desai N R, Majmudar P A. Pre-Clinical Evaluation of Corneal Healing and Safety of a Novel Topical Ocular Surface Cooling Device for Chronic Ocular Surface Pain. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC. 

Gupta P K, Rapuano C J, Garg S, Epitropoulos A T, Henderson B A, Galor A. Eight-Week Safety and Efficacy of a Novel Ocular Surface Cooling Device for Chronic Ocular Surface Pain: Double-Masked RCT Results. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC.

McDonald M B, Katz J, Epitropoulos A T, Gupta P K, Henderson B A, Galor A. One-Year Safety, Efficacy, and Patient Satisfaction in a Double-Masked RCT of a New Ocular Cooling Device for Chronic Ocular Surface Pain. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC.

Trattler W B, Hovanesian J A, Periman L M, Majmudar P A, Katz J, Henderson B A. Survey of the Prevalence and Management of Chronic Ocular Surface Pain (COSP) in US Eyecare Clinics. Accepted for presentation at: American Society of Cataract and Refractive Surgeons Annual Meeting; April 2026; Washington, DC.

Galor A, Henderson BA, Pflugfelder SC, White DE, Gupta PK, Periman LM, Chan AH, Salinas R, Stefater JA, Stryjewski T, Ifantides C. Prevalence and Management of Chronic Ocular Surface Pain in U.S. Eyecare Clinics. American Academy of Ophthalmology Annual Meeting. Orlando, FL. October 2025.